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Successful Treatment of Advanced Intrahepatic Cholangiocarcinoma With a High Tumor Mutational Burden and PD-L1 Expression by PD-1 Blockade Combined With Tyrosine Kinase Inhibitors: A Case Report

Advanced intrahepatic cholangiocarcinoma (iCCA) is not suitable for surgical treatment. Guided by the concept of precision medicine, preoperative systematic treatment may reshape the clinical outcomes of advanced intrahepatic cholangiocarcinoma patients. We describe the case of a 38-year-old female...

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Principais autores: Ze Zhang, Wenwen Zhang, Hongguang Wang, Bingyang Hu, Zhanbo Wang, Shichun Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-09-01
coleção:Frontiers in Immunology
Assuntos:
intrahepatic cholangiocarcinoma
immunotherapy
conversion therapy
PD-L1
TMB
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2021.744571/full
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