Luteolin mitigates proliferative vitreoretinopathy through inhibition of ERK1/2 signaling and epithelial–mesenchymal transition

AimTo investigate the inhibitory effect of luteolin on proliferative vitreoretinopathy (PVR) and explore its potential mechanism.MethodsHuman retinal pigment epithelial ARPE-19 cells were treated with luteolin (0–50 μM) to assess its effects on cell viability, migration, and TGF-β2–induced epithelia...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Lingdan Wu, Meiling Chen, Jinghua Chai, Yujie Tang, Qihua Xu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2026-02-01
Цуврал:	Frontiers in Pharmacology
Нөхцлүүд:	proliferative vitreoretinopathy epithelial-mesenchymal transition retinal pigment epithelial cell luteolin TGF-β2
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1634617/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!