Minoxidil ameliorates myelodysplastic syndrome by targeting Wnt4 while sparing normal hematopoiesis

Abstract Background Hematopoietic stem cells (HSCs) maintain blood production via tightly regulated differentiation. Disruptions at this level can lead to myelodysplastic syndromes (MDS), characterized by ineffective hematopoiesis and marrow failure. Despite its clinical use, the antihypertensive an...

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Detalhes bibliográficos

Principais autores:	Xiaoling Shi, Yushi Liu, Lejun Huang, Yuxin Ou, Xinyu Chen, Yiming Ling, Yiyue Zhang, Qing Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
coleção:	Cell Communication and Signaling
Assuntos:	Wnt4 Minoxidil MDS
Acesso em linha:	https://doi.org/10.1186/s12964-025-02615-z
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