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Wnt and β-Catenin Signaling in the Bone Metastasis of Prostate Cancer

Wnt family proteins and β-catenin are critical for the regulation of many developmental and oncogenic processes. Wnts are secreted protein ligands which signal using a canonical pathway, and involve the transcriptional co-activator β-catenin or non-canonical pathways that are independent of β-cateni...

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Main Authors: Zachary Kaplan, Steven P. Zielske, Kristina G. Ibrahim, Frank C. Cackowski
Format: Artigo
Language:Inglês
Published: MDPI AG 2021-10-01
Series:Life
Subjects:
Wnt
β-catenin
bone metastasis
prostate cancer
Wnt5A
breast cancer
Online Access:https://www.mdpi.com/2075-1729/11/10/1099
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