What does a modified-Fibonacci dose-escalation actually correspond to?
<p>Abstract</p> <p>Background</p> <p>In most phase I oncology trials, it is often stated that the dose increments follow a “modified-Fibonacci sequence”. This term, however, is vague.</p> <p>Methods</p> <p>To better characterize this sequence, we reviewed 81 phase I trials based on this concept.</p>...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2012-07-01
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| Serie: | BMC Medical Research Methodology |
| Soggetti: | |
| Accesso online: | http://www.biomedcentral.com/1471-2288/12/103 |
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