The role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury

Abstract Background Traumatic brain injury remains a significant cause of death and disability in the USA. Currently, there are no effective therapies to mitigate disability except for surgical interventions necessitating a need for continued research into uncovering novel therapeutic targets. In a...

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Autori principali:	Stephanie W. Lee, Juan Pablo de Rivero Vaccari, Jessie S. Truettner, W. Dalton Dietrich, Robert W. Keane
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2019-02-01
Serie:	Journal of Neuroinflammation
Soggetti:	Inflammasome ASC Pyroptosis Microglia Infiltrating leukocytes Traumatic brain injury
Accesso online:	http://link.springer.com/article/10.1186/s12974-019-1423-6
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