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Netosis and Inflammasomes in Large Vessel Occlusion Thrombi

The inflammatory response appears to play a critical role in clotting in which neutrophil extracellular traps (NETs) are the major drivers of thrombosis in acute ischemic stroke (AIS). The inflammasome is an innate immune complex involved in the activation of interleukin (IL)-18 and IL-1β through ca...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Stephanie H. Chen, Xavier O. Scott, Yoandy Ferrer Marcelo, Vania W. Almeida, Patricia L. Blackwelder, Dileep R. Yavagal, Eric C. Peterson, Robert M. Starke, W. Dalton Dietrich, Robert W. Keane, Juan Pablo de Rivero Vaccari
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-01-01
Schriftenreihe:Frontiers in Pharmacology
Schlagworte:
inflammation
stroke
inflammasome
thrombus
caspase-1
ASC
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fphar.2020.607287/full
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