Integrating single-cell RNA-seq and bulk RNA-seq to identify hub pathways and diagnostic biomarkers in active pulmonary tuberculosis
Abstract Background Tuberculosis (TB) continues to be a major global health challenge, with difficulties in distinguishing active TB (ATB) from latent TB infection (LTBI) and identifying early biomarkers for diagnosis. Methods This study integrated single-cell RNA sequencing (scRNA-seq) and bulk tra...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2026-02-01
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| Serie: | BMC Infectious Diseases |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s12879-026-12805-w |
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