BLM has Contrary Effects on Repeat-Mediated Deletions, based on the Distance of DNA DSBs to a Repeat and Repeat Divergence

Summary: Repeat-mediated deletions (RMDs) often involve repetitive elements (e.g., short interspersed elements) with sequence divergence that is separated by several kilobase pairs (kbps). We have examined RMDs induced by DNA double-strand breaks (DSBs) under varying conditions of repeat sequence di...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Carlos Mendez-Dorantes, L. Jillianne Tsai, Eva Jahanshir, Felicia Wednesday Lopezcolorado, Jeremy M. Stark
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2020-02-01
Schriftenreihe:	Cell Reports
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2211124720300012
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!