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The TUDOR domain of SMN is an H3K79 me1 histone mark reader

The survival of motor neuron (SMN) protein is depleted in spinal muscular atrophy (SMA) pathology and herein defined as the first reader of histone H3 mono-methylated on lysine 79 through its central TUDOR domain. Spinal muscular atrophy is the leading genetic cause of infant mortality and results f...

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Principais autores: Olivier Binda, Aimé Boris Kimenyi Ishimwe, Maxime Galloy, Karine Jacquet, Armelle Corpet, Amélie Fradet-Turcotte, Jocelyn Côté, Patrick Lomonte
Formato: Artigo
Idioma:Inglês
Publicado: Life Science Alliance LLC 2023-06-01
Series:Life Science Alliance
Acceso en liña:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202201752
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