Genetic polymorphism in untranslated regions of PRKCZ influences mRNA structure, stability and binding sites

Abstract Background Variations in untranslated regions (UTR) alter regulatory pathways impacting phenotype, disease onset, and course of disease. Protein kinase C Zeta (PRKCZ), a serine-threonine kinase, is implicated in cardiovascular, neurological and oncological disorders. Due to limited research...

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Hauptverfasser:	Aneela Mustafa, Maria Shabbir, Yasmin Badshah, Khushbukhat Khan, Fizzah Abid, Janeen H. Trembley, Tayyaba Afsar, Ali Almajwal, Suhail Razak
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-09-01
Schriftenreihe:	BMC Cancer
Schlagworte:	UTR PRKCZ Non-coding SNPs In-silico tools miRNA Oncological disorders
Online-Zugang:	https://doi.org/10.1186/s12885-024-12900-8
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