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Identification and analysis of oncogenic non-synonymous single nucleotide polymorphisms in the human NRAS gene: An exclusive in silico study

Background: N-ras protein is encoded by the NRAS gene and operates as GDP-GTP-controlled on/off switching. N-ras interacts with cellular signaling networks that regulate various cellular activities including cell proliferation and survival. The nonsynonymous single nucleotide polymorphism (nsSNPs)-m...

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Principais autores: Md. Mozibullah, Hadieh Eslampanah Seyedi, Marina Khatun, Md Solayman
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-06-01
Serier:Journal of Genetic Engineering and Biotechnology
Fag:
Cancer
In silico
nsSNPs
NRAS gene
Oncogenic
Polymorphism
Online adgang:http://www.sciencedirect.com/science/article/pii/S1687157X24000817
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