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The COP9 Signalosome: A Multi-DUB Complex

The COP9 signalosome (CSN) is a signaling platform controlling the cellular ubiquitylation status. It determines the activity and remodeling of ~700 cullin-RING ubiquitin ligases (CRLs), which control more than 20% of all ubiquitylation events in cells and thereby influence virtually any cellular pa...

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Bibliografiske detaljer
Principais autores: Wolfgang Dubiel, Supattra Chaithongyot, Dawadschargal Dubiel, Michael Naumann
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-07-01
Serier:Biomolecules
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Online adgang:https://www.mdpi.com/2218-273X/10/7/1082
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