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Generative diffusion model surrogates for mechanistic agent-based biological models

Mechanistic, multicellular, agent-based models are commonly used to investigate tissue, organ, and organism-scale biology at single-cell resolution. The Cellular-Potts Model (CPM) is a powerful and popular framework for developing and interrogating these models. CPMs become computationally expensive...

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Principais autores: Tien Comlekoglu, J Quetzalcoatl Toledo-Marín, Douglas W DeSimone, Shayn M Peirce, Geoffrey Fox, James A Glazier
Format: Artigo
Sprog:Inglês
Udgivet: IOP Publishing 2025-01-01
Serier:Machine Learning: Science and Technology
Fag:
generative
agent-based model
vasculogenesis
digital twin
denoising diffusion probabilistic model
denoising diffusion model
Online adgang:https://doi.org/10.1088/2632-2153/ae11f8
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