Generative diffusion model surrogates for mechanistic agent-based biological models

Mechanistic, multicellular, agent-based models are commonly used to investigate tissue, organ, and organism-scale biology at single-cell resolution. The Cellular-Potts Model (CPM) is a powerful and popular framework for developing and interrogating these models. CPMs become computationally expensive...

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Autors principals:	Tien Comlekoglu, J Quetzalcoatl Toledo-Marín, Douglas W DeSimone, Shayn M Peirce, Geoffrey Fox, James A Glazier
Format:	Artigo
Idioma:	Inglês
Publicat:	IOP Publishing 2025-01-01
Col·lecció:	Machine Learning: Science and Technology
Matèries:	generative agent-based model vasculogenesis digital twin denoising diffusion probabilistic model denoising diffusion model
Accés en línia:	https://doi.org/10.1088/2632-2153/ae11f8
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