Structure-Activity Relationships of the Bioactive Thiazinoquinone Marine Natural Products Thiaplidiaquinones A and B

In an effort to more accurately define the mechanism of cell death and to establish structure-activity relationship requirements for the marine meroterpenoid alkaloids thiaplidiaquinones A and B, we have evaluated not only the natural products but also dioxothiazine regioisomers and two precursor qu...

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主要な著者:	Jacquie L. Harper, Iman M. Khalil, Lisa Shaw, Marie-Lise Bourguet-Kondracki, Joëlle Dubois, Alexis Valentin, David Barker, Brent R. Copp
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2015-08-01
シリーズ:	Marine Drugs
主題:	thiaplidiaquinone Aplidium ascidian thiazinoquinone apoptosis Jurkat cytotoxicity malaria farnesyltransferase
オンライン･アクセス:	http://www.mdpi.com/1660-3397/13/8/5102
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