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Structure-Activity Relationships of the Bioactive Thiazinoquinone Marine Natural Products Thiaplidiaquinones A and B

In an effort to more accurately define the mechanism of cell death and to establish structure-activity relationship requirements for the marine meroterpenoid alkaloids thiaplidiaquinones A and B, we have evaluated not only the natural products but also dioxothiazine regioisomers and two precursor qu...

Deskribapen osoa

Gorde:
Egile Nagusiak: Jacquie L. Harper, Iman M. Khalil, Lisa Shaw, Marie-Lise Bourguet-Kondracki, Joëlle Dubois, Alexis Valentin, David Barker, Brent R. Copp
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2015-08-01
Saila:Marine Drugs
Gaiak:
thiaplidiaquinone
Aplidium
ascidian
thiazinoquinone
apoptosis
Jurkat
cytotoxicity
malaria
farnesyltransferase
Sarrera elektronikoa:http://www.mdpi.com/1660-3397/13/8/5102
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