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Trained immunity is induced in humans after immunization with an adenoviral vector COVID-19 vaccine

Background Heterologous effects of vaccines are mediated by “trained immunity,” whereby myeloid cells are metabolically and epigenetically reprogrammed, resulting in heightened responses to subsequent insults. Adenovirus vaccine vector has been reported to induce trained immunity in mice. Therefore,...

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書誌詳細
主要な著者: Dearbhla M. Murphy, Donal J. Cox, Sarah A. Connolly, Eamon P. Breen, Aenea A.I. Brugman, James J. Phelan, Joseph Keane, Sharee A. Basdeo
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2023-01-01
シリーズ:The Journal of Clinical Investigation
主題:
オンライン・アクセス:https://doi.org/10.1172/JCI162581
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