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Cardiomyocyte Atrophy, an Underestimated Contributor in Doxorubicin-Induced Cardiotoxicity

Left ventricular (LV) mass loss is prevalent in doxorubicin (DOX)-induced cardiotoxicity and is responsible for the progressive decline of cardiac function. Comparing with the well-studied role of cell death, the part of cardiomyocyte atrophy (CMA) playing in the LV mass loss is underestimated and t...

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Principais autores: De-Shu Chen, Jing Yan, Ping-Zhen Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-02-01
coleção:Frontiers in Cardiovascular Medicine
Assuntos:
doxorubicin
cardiotoxicity
cardiomyocyte atrophy
left ventricular mass loss
cell death
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcvm.2022.812578/full
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