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DNA hypermethylation: A novel mechanism of CREG gene suppression and atherosclerogenic endothelial dysfunction

Objective: Cellular repressor of E1A-stimulated genes (CREG), a vasculoprotective molecule, is significantly downregulated in atherosclerotic vessels through unclear mechanisms. While epigenetic regulation is involved in atherosclerosis development, it is not known if the CREG gene is epigenetically...

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Principais autores: Yanxia Liu, Xiaoxiang Tian, Shan Liu, Dan Liu, Yang Li, Meili Liu, Xiaolin Zhang, Chenghui Yan, Yaling Han
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-05-01
coleção:Redox Biology
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213231719313977
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