Branched‐chain α‐keto acids and glutamate/glutamine: Biomarkers of insulin resistance in childhood obesity

Abstract Objectives Insulin resistance (IR) in adolescents with obesity is associated with a sex‐dependent metabolic ‘signature’ comprising the branched‐chain amino acids (BCAAs), glutamate/glutamine, C3/C5 acylcarnitines and uric acid. Here, we compared the levels of branched‐chain α‐keto acids (BC...

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Autors principals:	Pinar Gumus Balikcioglu, Catherine Jachthuber Trub, Metin Balikcioglu, Olga Ilkayeva, Phillip J. White, Michael Muehlbauer, James R. Bain, Sarah Armstrong, Michael Freemark
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2023-01-01
Col·lecció:	Endocrinology, Diabetes & Metabolism
Matèries:	branched‐chain amino acid branched‐chain α‐keto acid childhood obesity insulin resistance metabolomics
Accés en línia:	https://doi.org/10.1002/edm2.388
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