Iso-mukaadial acetate and ursolic acid acetate bind to Plasmodium Falciparum heat shock protein 70: towards targeting parasite protein folding pathway

Abstract Plasmodium falciparum is the most lethal malaria parasite. P. falciparum Hsp70 (PfHsp70) is an essential molecular chaperone (facilitates protein folding) and is deemed a prospective antimalarial drug target. The present study investigates the binding capabilities of select plant derivative...

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Egile Nagusiak:	Francis Opoku, Penny Govender, Addmore Shonhai, Mthokozisi BC Simelane
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2024-03-01
Saila:	BMC Chemistry
Gaiak:	Heat shock protein Inhibitor iso-mukaadial acetate Ursolic acid acetate Plasmodium Falciparum
Sarrera elektronikoa:	https://doi.org/10.1186/s13065-024-01159-6
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