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Iso-mukaadial acetate and ursolic acid acetate bind to Plasmodium Falciparum heat shock protein 70: towards targeting parasite protein folding pathway

Abstract Plasmodium falciparum is the most lethal malaria parasite. P. falciparum Hsp70 (PfHsp70) is an essential molecular chaperone (facilitates protein folding) and is deemed a prospective antimalarial drug target. The present study investigates the binding capabilities of select plant derivative...

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Bibliográfalaš dieđut
Váldodahkkit: Francis Opoku, Penny Govender, Addmore Shonhai, Mthokozisi BC Simelane
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2024-03-01
Ráidu:BMC Chemistry
Fáttát:
Liŋkkat:https://doi.org/10.1186/s13065-024-01159-6
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