Assessing the efficacy of iso-mukaadial acetate and betulinic acid against selected Plasmodium falciparum glycolytic pathway proteins: in silico and in vitro studies

Abstract Malaria is the extensive health concern in sub-Saharan Africa, with Plasmodium falciparum being the most lethal strain. The continued emergence of drug-resistant P. falciparum advocates for the development of new antimalarials. Our current study aimed to effectively explore the interaction...

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Principais autores:	Lindiwe Khumbuzile Zuma, Ofentse Jacob Pooe, Nonduduzo Hlengiwe Mabaso, John Alake, Vincent A. Obakachi, Sinethemba Yakobi, Nothando Gasa, Rajshekhar Karpoormath, Mthokozisi Simelane
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2025-01-01
Serija:	BMC Chemistry
Teme:	Malaria Plasmodium falciparum Medicinal compounds Interaction studies
Online dostop:	https://doi.org/10.1186/s13065-025-01380-x
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