Mechanistic insights into multiple-step transport of mitochondrial ADP/ATP carrier

The ADP/ATP carrier (AAC) is crucial for mitochondrial functions by importing ADP and exporting ATP across the inner mitochondrial membrane. However, the mechanism of highly specific ADP recognition and transport by AAC remains largely elusive. In this work, spontaneous ADP binding process to the gr...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Shihao Yao, Qiuzi Yi, Boyuan Ma, Xiaoting Mao, Ye Chen, Min-Xin Guan, Xiaohui Cang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Association for the Advancement of Science (AAAS) 2022-01-01
Цуврал:	Computational and Structural Biotechnology Journal
Нөхцлүүд:	Transporter Mitochondrial ADP ATP translocases Solute carrier family 25, molecular dynamics simulation Substrate recognition
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2001037022001076
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!