Mechanistic insights into multiple-step transport of mitochondrial ADP/ATP carrier

The ADP/ATP carrier (AAC) is crucial for mitochondrial functions by importing ADP and exporting ATP across the inner mitochondrial membrane. However, the mechanism of highly specific ADP recognition and transport by AAC remains largely elusive. In this work, spontaneous ADP binding process to the gr...

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Hlavní autoři:	Shihao Yao, Qiuzi Yi, Boyuan Ma, Xiaoting Mao, Ye Chen, Min-Xin Guan, Xiaohui Cang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Association for the Advancement of Science (AAAS) 2022-01-01
Edice:	Computational and Structural Biotechnology Journal
Témata:	Transporter Mitochondrial ADP ATP translocases Solute carrier family 25, molecular dynamics simulation Substrate recognition
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2001037022001076
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