Mechanistic insights into multiple-step transport of mitochondrial ADP/ATP carrier

The ADP/ATP carrier (AAC) is crucial for mitochondrial functions by importing ADP and exporting ATP across the inner mitochondrial membrane. However, the mechanism of highly specific ADP recognition and transport by AAC remains largely elusive. In this work, spontaneous ADP binding process to the gr...

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מידע ביבליוגרפי

Principais autores:	Shihao Yao, Qiuzi Yi, Boyuan Ma, Xiaoting Mao, Ye Chen, Min-Xin Guan, Xiaohui Cang
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Association for the Advancement of Science (AAAS) 2022-01-01
סדרה:	Computational and Structural Biotechnology Journal
נושאים:	Transporter Mitochondrial ADP ATP translocases Solute carrier family 25, molecular dynamics simulation Substrate recognition
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2001037022001076
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