The free energy barrier for arginine gating charge translation is altered by mutations in the voltage sensor domain.
The gating of voltage-gated ion channels is controlled by the arginine-rich S4 helix of the voltage-sensor domain moving in response to an external potential. Recent studies have suggested that S4 moves in three to four steps to open the conducting pore, thus visiting several intermediate conformati...
Na minha lista:
| Principais autores: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2012-01-01
|
| Serier: | PLoS ONE |
| Online adgang: | http://europepmc.org/articles/PMC3477161?pdf=render |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|