The deubiquitinase OTUD4 inhibits the expression of antimicrobial peptides in Paneth cells to support intestinal inflammation and bacterial infection

Dysfunction of the intestinal epithelial barrier causes microbial invasion that would lead to inflammation in the gut. Antimicrobial peptides (AMPs) are essential components of the intestinal epithelial barrier, while the regulatory mechanisms of AMPs expression are not fully characterized. Here, we...

Полное описание

Библиографические подробности

Главные авторы:	Keying Yu, Yu-Yao Guo, Tianzi Liuyu, Peng Wang, Zhi-Dong Zhang, Dandan Lin, Bo Zhong
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2023-06-01
Серии:	Cell Insight
Предметы:	OTUD4 Colitis Bacterial infection Antimicrobial peptides MyD88 Deubiquitination
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S277289272300024X
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!