The deubiquitinase OTUD3 plays a neuroprotective role by reducing ferroptosis induced by cerebral ischaemia reperfusion via stabilizing PLK1 via deubiquitination

Abstract Ischaemic stroke is one of the most common serious diseases observed in elderly people, which is caused by ischaemia‐reperfusion (I/R) injury. Ovarian tumour domain‐containing protein 3 (OTUD3) is a member of the ovarian tumour proteases (OTUs) family of deubiquitination enzymes located in...

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Autores principales:	Jing Cheng, Qi Tian, Hao‐Ran Lu, Hong‐Xiang Jiang, Xiao‐Hong Qin, Yan‐Qin Fan, Zhi‐Biao Chen, Li‐Quan Wu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2025-05-01
Colección:	Clinical and Translational Medicine
Materias:	deubiquitination ischaemia‐reperfusion injury neuroprotection OTUD3 PLK1
Acceso en línea:	https://doi.org/10.1002/ctm2.70347
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!