Branched‐Chain Amino Acids Mediate the Regulation of SACE_Lrp on the Aminotransferase IlvE Involved in Erythromycin Biosynthesis in Saccharopolyspora erythraea

ABSTRACT Erythromycin is a broad‐spectrum polyketide antibiotic which can be obtained mainly through biosynthesis. The catabolic pathway of branched‐chain amino acids (BCAAs) significantly influences the biosynthesis of erythromycin. However, the regulatory mechanisms controlling the BCAA catabolic...

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Autori principali:	Xinlu Cai, Lijuan Tang, Yinuo Liu, Youquan Zou, Xueyan Li, Haoyang He, Youya Tang, Endong Yang, Buchang Zhang, Jing Liu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2026-04-01
Serie:	Microbial Biotechnology
Soggetti:	aminotransferase IlvE branched‐chain amino acid erythromycin biosynthesis SACE_Lrp regulator
Accesso online:	https://doi.org/10.1111/1751-7915.70344
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