Branched‐Chain Amino Acids Mediate the Regulation of SACE_Lrp on the Aminotransferase IlvE Involved in Erythromycin Biosynthesis in Saccharopolyspora erythraea

ABSTRACT Erythromycin is a broad‐spectrum polyketide antibiotic which can be obtained mainly through biosynthesis. The catabolic pathway of branched‐chain amino acids (BCAAs) significantly influences the biosynthesis of erythromycin. However, the regulatory mechanisms controlling the BCAA catabolic...

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Hlavní autoři:	Xinlu Cai, Lijuan Tang, Yinuo Liu, Youquan Zou, Xueyan Li, Haoyang He, Youya Tang, Endong Yang, Buchang Zhang, Jing Liu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2026-04-01
Edice:	Microbial Biotechnology
Témata:	aminotransferase IlvE branched‐chain amino acid erythromycin biosynthesis SACE_Lrp regulator
On-line přístup:	https://doi.org/10.1111/1751-7915.70344
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