QR Code

A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer

Abstract Background Prostate cancer is a major cause of cancer morbidity and mortality in men worldwide. Androgen deprivation therapy (ADT) has proven effective in early-stage androgen-sensitive disease, but prostate cancer gradually develops into an androgen-resistant metastatic state in the vast m...

Description complète

Enregistré dans:
Auteurs principaux: Ioanna Mourkioti, Aikaterini Polyzou, Dimitris Veroutis, George Theocharous, Nefeli Lagopati, Emanuela Gentile, Vasiliki Stravokefalou, Dimitris-Foivos Thanos, Sophia Havaki, Dimitris Kletsas, Theocharis Panaretakis, Christopher J. Logothetis, Dimitris Stellas, Russell Petty, Giovanni Blandino, Angelos Papaspyropoulos, Vassilis G. Gorgoulis
Format: Artigo
Langue:Inglês
Publié: BMC 2023-07-01
Collection:Journal of Experimental & Clinical Cancer Research
Sujets:
Prostate cancer
AR signaling blockade
Enzalutamide
GATA2-CDC6 axis
Cellular senescence
Accès en ligne:https://doi.org/10.1186/s13046-023-02769-z
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires