क्यूआर कोड

A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer

Abstract Background Prostate cancer is a major cause of cancer morbidity and mortality in men worldwide. Androgen deprivation therapy (ADT) has proven effective in early-stage androgen-sensitive disease, but prostate cancer gradually develops into an androgen-resistant metastatic state in the vast m...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Ioanna Mourkioti, Aikaterini Polyzou, Dimitris Veroutis, George Theocharous, Nefeli Lagopati, Emanuela Gentile, Vasiliki Stravokefalou, Dimitris-Foivos Thanos, Sophia Havaki, Dimitris Kletsas, Theocharis Panaretakis, Christopher J. Logothetis, Dimitris Stellas, Russell Petty, Giovanni Blandino, Angelos Papaspyropoulos, Vassilis G. Gorgoulis
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BMC 2023-07-01
श्रृंखला:Journal of Experimental & Clinical Cancer Research
विषय:
Prostate cancer
AR signaling blockade
Enzalutamide
GATA2-CDC6 axis
Cellular senescence
ऑनलाइन पहुंच:https://doi.org/10.1186/s13046-023-02769-z
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