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CCAAT/enhancer-binding protein alpha (CEBPA) gene haploinsufficiency does not alter hematopoiesis or induce leukemia in Lck-CALM/AF10 transgenic mice

Although rare, CALM/AF10 is a chromosomal rearrangement found in immature T-cell acute lymphoblastic leukemia (T-ALL), acute myeloid leukemia, and mixed phenotype acute leukemia of T/myeloid lineages with poor prognosis. Moreover, this translocation is detected in 50% of T-ALL patients with gamma/de...

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Principais autores: A.P. Lange, L.Y. Almeida, C.L. Araújo Silva, P.S. Scheucher, F. Chahud, A. Krause, S.K. Bohlander, E.M. Rego
格式: Artigo
語言:Inglês
出版: Associação Brasileira de Divulgação Científica
叢編:Brazilian Journal of Medical and Biological Research
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在線閱讀:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000600604&lng=en&tlng=en
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