CCAAT/enhancer-binding protein alpha (CEBPA) gene haploinsufficiency does not alter hematopoiesis or induce leukemia in Lck-CALM/AF10 transgenic mice
Although rare, CALM/AF10 is a chromosomal rearrangement found in immature T-cell acute lymphoblastic leukemia (T-ALL), acute myeloid leukemia, and mixed phenotype acute leukemia of T/myeloid lineages with poor prognosis. Moreover, this translocation is detected in 50% of T-ALL patients with gamma/de...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
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Associação Brasileira de Divulgação Científica
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| Edice: | Brazilian Journal of Medical and Biological Research |
| Témata: | |
| On-line přístup: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000600604&lng=en&tlng=en |
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