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The Dynamics of SecM-Induced Translational Stalling

SecM is an E. coli secretion monitor capable of stalling translation on the prokaryotic ribosome without cofactors. Biochemical and structural studies have demonstrated that the SecM nascent chain interacts with the 50S subunit exit tunnel to inhibit peptide bond formation. However, the timescales a...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Albert Tsai, Guy Kornberg, Magnus Johansson, Jin Chen, Joseph D. Puglisi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2014-06-01
Rangatū:Cell Reports
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211124714003350
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