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Macrolide resistance in Helicobacter pylori: rapid detection of point mutations and assays of macrolide binding to ribosomes.

Resistance of Helicobacter pylori to macrolides is a major cause of failure of eradication therapies. Single base substitutions in the H. pylori 23S rRNA genes have been associated with macrolide resistance in the United States. Our goal was to extend this work to European strains, to determine the...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Occhialini, A, Urdaci, M, Doucet-Populaire, F, Bébéar, C M, Lamouliatte, H, Mégraud, F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420046/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.12.2724
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