Body‐Wide Inactivation of the Myc‐Like Mlx Transcription Factor Network Accelerates Aging and Increases the Lifetime Cancer Incidence

Abstract The “Mlx” and “Myc” transcription factor networks cross‐communicate and share many common gene targets. Myc's activity depends upon its heterodimerization with Max, whereas the Mlx Network requires that the Max‐like factor Mlx associate with the Myc‐like factors MondoA or ChREBP. The curren...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Huabo Wang, Taylor Stevens, Jie Lu, Alexander Roberts, Clinton Van't Land, Radhika Muzumdar, Zhenwei Gong, Jerry Vockley, Edward V. Prochownik
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Wiley 2024-09-01
Sarja:	Advanced Science
Aiheet:	glycolysis mitochondria reactive oxygen species TCA cycle telomeres Warburg effect
Linkit:	https://doi.org/10.1002/advs.202401593
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!