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JP4-039 Mitigates Cisplatin-Induced Acute Kidney Injury by Inhibiting Oxidative Stress and Blocking Apoptosis and Ferroptosis in Mice

Cisplatin is a commonly used chemotherapeutic agent in the treatment of a wide array of cancers. Due to its active transport into the kidney proximal tubule cells, cisplatin treatment can cause a buildup of this nephrotoxic compound in the kidney, resulting in acute kidney injury (AKI). About 30% of...

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Autori principali: Merlin Airik, Kacian Clayton, Peter Wipf, Rannar Airik
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2024-12-01
Serie:Antioxidants
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Accesso online:https://www.mdpi.com/2076-3921/13/12/1534
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