Overexpression of the RNA-binding protein NrdA affects global gene expression and secondary metabolism in Aspergillus species

ABSTRACT RNA-binding protein Nrd1 plays a role in RNA polymerase II transcription termination. In this study, we showed that the orthologous NrdA is important in global mRNA expression and secondary metabolism in Aspergillus species. We constructed an nrdA conditional expression strain using the Tet...

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Autori principali:	Chihiro Kadooka, Kosuke Izumitsu, Teigo Asai, Kentaro Hiramatsu, Kazuki Mori, Kayu Okutsu, Yumiko Yoshizaki, Kazunori Takamine, Masatoshi Goto, Hisanori Tamaki, Taiki Futagami
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2025-02-01
Serie:	mSphere
Soggetti:	Aspergillus RNA-binding protein NrdA gene expression secondary metabolism
Accesso online:	https://journals.asm.org/doi/10.1128/msphere.00849-24
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