The dyskerin ribonucleoprotein complex as an OCT4/SOX2 coactivator in embryonic stem cells

Acquisition of pluripotency is driven largely at the transcriptional level by activators OCT4, SOX2, and NANOG that must in turn cooperate with diverse coactivators to execute stem cell-specific gene expression programs. Using a biochemically defined in vitro transcription system that mediates OCT4/...

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Autores principales:	Yick W Fong, Jaclyn J Ho, Carla Inouye, Robert Tjian
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	eLife Sciences Publications Ltd 2014-11-01
Colección:	eLife
Materias:	transcriptional coactivator pluripotency embryonic stem cell non-coding RNA induced pluripotent stem cell priviledged somatic cell state
Acceso en línea:	https://elifesciences.org/articles/03573
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