The dyskerin ribonucleoprotein complex as an OCT4/SOX2 coactivator in embryonic stem cells

Acquisition of pluripotency is driven largely at the transcriptional level by activators OCT4, SOX2, and NANOG that must in turn cooperate with diverse coactivators to execute stem cell-specific gene expression programs. Using a biochemically defined in vitro transcription system that mediates OCT4/...

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Hlavní autoři:	Yick W Fong, Jaclyn J Ho, Carla Inouye, Robert Tjian
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2014-11-01
Edice:	eLife
Témata:	transcriptional coactivator pluripotency embryonic stem cell non-coding RNA induced pluripotent stem cell priviledged somatic cell state
On-line přístup:	https://elifesciences.org/articles/03573
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