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Optimizing the dosing schedule of l-asparaginase improves its anti-tumor activity in breast tumor-bearing mice
Proliferation of acute lymphoblastic leukemic cells is nutritionally dependent on the external supply of asparagine. l-asparaginase, an enzyme hydrolyzing l-asparagine in blood, is used for treatment of acute lymphoblastic leukemic and other related blood cancers. Although previous studies demonstra...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2018-04-01
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| Col·lecció: | Journal of Pharmacological Sciences |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S1347861318300458 |
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