Mitochondrial base editing: from principle, optimization to application
Abstract In recent years, mitochondrial DNA (mtDNA) base editing systems have emerged as bioengineering tools. DddA-derived cytosine base editors (DdCBEs) have been developed to specifically induce C-to-T conversion in mtDNA by the fusion of sequence-programmable transcription activator-like effecto...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2025-01-01
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| シリーズ: | Cell & Bioscience |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1186/s13578-025-01351-8 |
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