Effect of PHF-1 hyperphosphorylation on the seeding activity of C-terminal Tau fragments
Abstract Tau proteins as neurofibrillary tangles are one of the molecular hallmarks of Alzheimer’s disease (AD) and play a central role in tauopathies, a group of age-related neurodegenerative disorders. The filament cores from diverse tauopathies share a common region of tau consisting of the R3-R4...
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| Автори: | , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Nature Portfolio
2025-03-01
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| Серія: | Scientific Reports |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1038/s41598-025-91867-3 |
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