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Phosphorylation at Ser26 in the ATP-binding site of Ca2+/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity

CaMKII (Ca2+/calmodulin-dependent kinase II) is a serine/threonine phosphotransferase that is capable of long-term retention of activity due to autophosphorylation at a specific threonine residue within each subunit of its oligomeric structure. The γ isoform of CaMKII is a significant regulat...

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Autores principales: Mehtap Yilmaz, Samudra S. Gangopadhyay, Paul Leavis, Zenon Grabarek, Kathleen G. Morgan
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press 2013-02-01
Colección:Bioscience Reports
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Acceso en línea:http://www.bioscirep.org/bsr/033/e024/bsr033e024.htm
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