Chemotranscriptomic Profiling Defines Drug-Specific Signatures of the Glycopeptide Antibiotics Dalbavancin, Vancomycin and Chlorobiphenyl-Vancomycin in a VanB-Type-Resistant Streptomycete

Dalbavancin, vancomycin and chlorobiphenyl-vancomycin share a high degree of structural similarity and the same primary mode of drug action. All inhibit bacterial cell wall biosynthesis through complexation with intermediates in peptidoglycan biosynthesis mediated via interaction with peptidyl-d-ala...

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Váldodahkkit:	Andy Hesketh, Giselda Bucca, Colin P. Smith, Hee-Jeon Hong
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2021-02-01
Ráidu:	Frontiers in Microbiology
Fáttát:	glycopeptide antibiotic resistance vancomycin dalbavancin chemotranscriptomics
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.641756/full
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