miRNA-Based Rapid Differentiation of Purified Neurons from hPSCs Advancestowards Quick Screening for Neuronal Disease Phenotypes In Vitro

Obtaining differentiated cells with high physiological functions by an efficient, but simple and rapid differentiation method is crucial for modeling neuronal diseases in vitro using human pluripotent stem cells (hPSCs). Currently, methods involving the transient expression of one or a couple of tra...

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Autors principals:	Mitsuru Ishikawa, Takeshi Aoyama, Shoichiro Shibata, Takefumi Sone, Hiroyuki Miyoshi, Hirotaka Watanabe, Mari Nakamura, Saori Morota, Hiroyuki Uchino, Andrew S. Yoo, Hideyuki Okano
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2020-02-01
Col·lecció:	Cells
Matèries:	human pluripotent stem cell excitatory neuron neurogenin2 microrna-9/9* microrna-124 alzheimer’s disease presenilin1 presenilin2
Accés en línia:	https://www.mdpi.com/2073-4409/9/3/532
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