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Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy

Abstract Spinal and bulbar muscular atrophy (SBMA) is an X-linked, neuromuscular neurodegenerative disease for which there is no cure. The disease is characterized by a selective decrease in fast-muscle power (e.g., tongue pressure, grip strength) accompanied by a selective loss of fast-twitch muscl...

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Principais autores: Elana Molotsky, Yuhong Liu, Andrew P. Lieberman, Diane E. Merry
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-07-01
coleção:Acta Neuropathologica Communications
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Acesso em linha:https://doi.org/10.1186/s40478-022-01402-y
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